Africatown Cannabis Guide: Mobile, Alabama

Mobile is Alabama's only saltwater port city, sitting at the mouth of Mobile Bay where the Mobile and Tensaw rivers meet the Gulf. Shipbuilding and maritime employers, including Austal USA, anchor much of the local workforce and patient base. RJK Holdings AL has planned a location here alongside sites in Oxford and Daphne, about 30 miles east across the bay. As of this writing we do not have confirmation that the Mobile store had opened; check directly with RJK Holdings AL or the AMCC for current status.
Until a local counter is confirmed, the closest working option has been Montgomery, roughly 170 miles north via I-65 (about 2 hours 45 minutes).
No address for the planned RJK Holdings AL storefront had been published as of this writing, so it is unclear whether it will land downtown near the port district or along a retail corridor like Airport Boulevard or Government Street. Once open, expect the same card-and-ID check-in other new Alabama stores have used, with cash preferred given limited card-processing options in cannabis retail. Beyond Austal USA's shipyards, the Alabama State Port Authority and a cluster of downtown medical offices round out the local patient base likely to be watching for an opening date.
Every rule about eligibility is a statewide fact; everything about cards, fees, products, and dosing limits lives in the statewide guide above instead.

Alabama's medical cannabis program is real but still very young. The Darren Wesley 'Iq' Holley Compassion Act passed in 2021 and created the Alabama Medical Cannabis Commission (AMCC), but license awards were tied up in litigation for years afterward. That changed on December 11, 2025, when the AMCC voted to approve dispensary licenses, and on January 8, 2026, three companies were issued licenses: CCS of Alabama, GP6 Wellness, and RJK Holdings AL. A fourth award, to Yellowhammer, was stayed pending an administrative challenge.
Callie's Apothecary, operated by CCS of Alabama, opened in Montgomery on June 4, 2026 as the state's first legally operating dispensary. A second Callie's opened in Talladega on August 28, 2026, and a third, in Bessemer near Birmingham, was expected in September 2026. GP6 Wellness has been building out BamaBloom dispensaries in Athens and Birmingham, also targeted for September 2026, and RJK Holdings AL has approved sites planned for Oxford, Mobile, and Daphne. The AMCC's full approved dispensing list also includes Attalla and Cullman. Integrated cultivation-through-retail licenses remained under administrative review in 2026.
Recreational cannabis is illegal statewide - a misdemeanor on a first personal-use offense, with felony exposure for repeat or larger-quantity possession. Only registered patients with a valid Alabama medical cannabis card may purchase, and only in person; the program does not allow delivery.
Separately, hemp-derived THC products (HB 445, fully effective January 2026) are regulated by the ABC Board - sold only in licensed stores to buyers 21+, capped at 10 mg THC per serving and 40 mg per package, no delivery. Smokable hemp and THC vapes are banned outright, with felony exposure for sellers since July 2025. This is a separate system from the AMCC medical program.

Alabama's licensed retail market only began operating in June 2026, so available brands are limited and will keep changing. The three companies holding dispensary licenses are CCS of Alabama (Callie's Apothecary), GP6 Wellness (BamaBloom), and RJK Holdings AL. A fourth award, to Yellowhammer, remains stayed pending an administrative challenge. Ask dispensary staff which licensed processor supplied a given product and request the batch's independent lab results before buying - required on every approved product.

Alabama's rollout has moved from zero open stores to a handful in under three months: Montgomery in June 2026, Talladega in August, and a wave of Birmingham-metro, Athens, and Gulf Coast openings targeted for September. Integrated cultivation-to-retail licenses remain stuck in administrative review, and the Yellowhammer license stays stayed pending appeal. Expect the approved-city list to keep growing through the rest of 2026, with Southeast Alabama and the Shoals the most likely gaps to close next given how many cities in this guide still have no nearby counter.